Acupuncture for Overactive Bladder
To assess the effectiveness of acupuncture in treating
female adult with overactive bladder. After we excluded other causes for
storage symptoms, a total of 240 consecutive female patients with overactive
bladder were enrolled and completed all aspects of this prospective randomized
controlled trial, of which 118 cases were randomly assigned to receive a weekly
acupuncture treatment (intervention group), while the other 122 cases were
given a pharmacological treatment of oral tolterodine tartrate 2 mg twice
daily (control group) for 4 weeks. Data on urgency, incontinence,
micturition frequency, nocturia episodes and voided volume were collected and
statistically analyzed before and after 4 weekly acupuncture treatments or
4 weeks' pharmacological treatment using a 3-day micturition diary. The
two groups of female patients with overactive bladder were given treatment with
weekly acupuncture (n = 118), oral tolterodine tartrate
(n = 122) for 4 weeks respectively. At weeks 4, subjects in both
intervention and control groups had significant decreases in number of urinary
urgency episodes, incontinence episodes, daytime frequency, nocturia episodes
and increase in volume voided per micturition without a significant difference
in the changes of overactive bladder symptoms between the groups. There were no
serious adverse events during the study. This randomized controlled trial
demonstrates that acupuncture is safe with significant improvements in patient
assessment of overactive bladder symptoms and may be considered a clinically
alternative treatment for overactive bladder in female adult.
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