GB 20 Treats Disorders of Cerebral Circulation
The acupoint GB20 is known to affect vertebrobasilar blood
flow regulation. However, no previous study has used transcranial Doppler
imaging to examine whether acupuncture at GB20 has a selective effect on blood
flow in various cerebral arteries, such as the basilar artery (BA) and the
middle cerebral arteries (MCAs). Therefore, this study sought to determine the
specific effects of GB20 acupuncture on cerebral blood flow (CBF). Blood flow
velocity and CO2 reactivity were measured by transcranial Doppler
imaging with a 2-MHz pulsed Doppler probe observed through both temporal
windows for the MCAs and through the suboccipital window for the BA before and
after GB20 acupuncture treatment in 15 healthy young male volunteers. The
changes in hyperventilation-induced CO2 reactivity and corrected
blood flow velocities at 40 mmHg (CV40) were assessed for the BA and both MCAs.
Blood pressure and heart rate were measured before and after the acupuncture
treatment. The study showed that CO2 reactivity in the BA increased
significantly after GB20 acupuncture treatment compared with baseline (p=0.041).
In contrast, CO2 reactivity in both MCAs remained unchanged. The
CV40 in the BA and the MCAs showed no change after the GB20 acupuncture
treatment. The mean heart rate decreased significantly after the GB20 acupuncture,
whereas the mean blood pressure showed no change. This study demonstrated that acupuncture
treatment on GB20 increases CO2 reactivity specifically in the BA,
with no effect in the MCAs. These results clinically support the use of GB20 to
treat disorders of posterior cerebral circulation and support the idea that
particular acupoints affect specific brain regions and cerebral arteries.
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