Gan
Cao and Drug-Herb Interactions
Liquorice is the root of Glycyrrhiza
uralensis Fisch. or Glycyrrhiza glabra L., Leguminosae. It is a
widely used herbal medicine native to southern Europe and parts of Asia and has
beneficial applications in both the medicinal and the confectionery sectors.
Unlike its usage in Europe, liquorice in traditional Chinese medicine is
commonly combined with other herbs in a single prescription, as a unique “guide
drug” to enhance the effectiveness of other ingredients, to reduce toxicity,
and to improve flavor in almost half of Chinese herbal formulas. A review on
phytochemical and pharmacological research to explain this unique “guide”
effect is suggested for future investigations.
Can Cao and its related drug-herb
interactions are reviewed in here.
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