Chinese Medicine Could Really Fight the Flu...
and
Possibly Treat Ebola
For centuries, traditional Chinese
medicine practitioners have given their patients honeysuckle, often in the form
of tea, to help alleviate certain ailments. Now, researchers think that this
age-old practice may have been on to something. A molecule within the plant has
been found to directly target influenza, making it a potential treatment option
for the troublesome virus.
That's at least according to a study
recently published in the journal Cell Research, which details how the molecule
MIR2911 seems to specifically target the working of the influenza-A virus (IAV)
- a type flu virus specifically associated with the avian, Spanish, and swine
flu.
What's bizarre is that, according to
the researchers, the boiling process of honeysuckle is the same reason that
scientists have largely ignored traditional Chinese medicine.
"It is commonly believed that
[beneficial molecules] will be destroyed during this process. Indeed, our data
showed that most [molecules] enriched in honeysuckle were degraded during the
boiling process," the authors wrote.
However, it was found that MIR2911
is selectively retained, as it appears unusually resistant to the damages of
boiling. In this case, Chinese medicine was hitting the nail on the head by
serving the medicinal plant as a tea.
To determine how exactly the
molecule helps fights an influenza infection, researchers delivered boiled
honeysuckle to a group of lab mice in the form of a soup. They quickly found
that in infected mice, MIR2911 was targeting two genes associated with viral
replication - PB2 and NS1 - binding to their messenger RNAs and essentially
getting in the way of the replication process. Unable to reproduce and spread
in the body, the virus then simply dies out.
The researchers call MIR2911 a
"virological penicillin," as it is an exclusive example of a natural
product directly targeting a wide variety of virus strains.
Stunningly, according to the team, an ongoing study
capitalizing on these recent results has revealed that MIR2911 even targets the
workings of the Ebola virus - a deadly disease that is threatening the world
through its West African pandemic. Still, it's improtant to note that the study
is far from complete and the results are nowhere near concrete.
Source of the story is here.
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