Si Jun Zi Tang for Intestinal Obstruction

Si Jun Zi Tang for Intestinal Obstruction

Intestinal obstruction is a common disease requiring abdominal surgery with significant morbidity and mortality. Currently, effective medical treatments for obstruction, other than surgical resection or decompression, do not exist. Si-Jun-Zi Decoction is a famous Chinese medicine used to tonify qi and invigorate the functions of the spleen. Modern pharmacological studies show that this prescription can improve gastrointestinal function and strengthen immune function. This study investigated the effects of Si-Jun-Zi Decoction on the restoration of intestinal function after the relief of obstruction in a rabbit model. The researchers found that Si-Jun-Zi Decoction could reduce intestinal mucosal injury while promoting the recovery of the small intestine. Further, Si-Jun-Zi Decoction could regulate the intestinal immune system. Their results suggest that Si-Jun-Zi Decoction promotes the restoration of intestinal function after obstruction by regulating intestinal homeostasis. Our observations indicate that Si-Jun-Zi Decoction is potentially a therapeutic medicine for intestinal obstruction.

Xiangyang Yu, Zhigang Cui, Zhenli Zhou, Tao Shan, Donghua Li, and Naiqiang Cui.  Si-Jun-Zi Decoction Treatment Promotes the Restoration of Intestinal Function after Obstruction by Regulating Intestinal Homeostasis Evidence-Based Complementary and Alternative Medicine, Volume 2014, Article ID 928579.