Popular Chinese Herbs for Sjögren's Syndrome
This large-scale survey aimed to evaluate frequencies and
patterns of Chinese herbal medicine (CHM) used for Sjögren's syndrome (SS) in
Taiwan by analyzing the National Health Insurance Research Database (NHIRD) for
cases in which CHM was used as an alternative therapy to Western medicine for
improving patients' discomforts. We analyzed cases of SS principal diagnosis
(ICD-9:710.2) with a catastrophic illness certificate (CIC) in traditional
Chinese medicine (TCM) outpatient clinics from three cohorts of the
Longitudinal Health Insurance Database (LHID) in the NHIRD between 2002 and
2011. CHM prescription patterns for SS were evaluated from claimed visitation
files and corresponding prescription files. There were 15,914 SS patients with
CIC (SS/CIC), and we found only 130 SS/CIC cases visiting TCM clinics in
LHID2000, 133 in LHID2005, and 126 in LHID2010. After removing duplicate data,
366 SS/CIC and 4,867 visits were analyzed. The 50-59 year age group showed the
highest ratio (29.51%) in both women and men. "Qi-Ju-Di-Huang-Wan"
and "Xuan-Shen" (Scrophularia ningpoensis Hemsl.) was the most
commonly used formula and single herb, respectively. "Qi-Ju-Di-Huang-Wan,
Gan-Lu-Yin, Xuan-Shen, Mai-Men-Dong (Ophiopogon japonicus (L. f.) Ker-Gawl.),
and Sheng-Di-Huang (raw Rehmannia glutinosa Libosch)" were the core
pattern prescriptions in treating SS/CIC.
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