Da Cheng Qi Tang and Gastrointestinal Motility
The aim of this study was to investigate the effect of Da-Cheng-Qi-Tang
(DCQT) on the gastrointestinal motility after abdominal surgery in humans. Thirty-three
patients with abdominal surgery and 36 patients with cholecystectomy were
divided into DCQT and control groups at random. Electrogastrography (EGG) and
antroduodenojejunal manometry were performed and the level of plasma ghrelin
were measured by ELISA. On the operative day, the ratio of EGG normal slow
waves in DCQT group was higher than in control group (p<0.05). The power of
EGG in DCQT group was higher than in control group on the 2nd and 3rd postoperative
day (p<0.05). The percentage of normal bowel peristalsis was significantly
higher in the DCQT group than in control group (p<0.01). On the 1st and 2nd
postoperative day, the power of Phase III of migrating motor complex (MMC) in
the proximal jejunum in DCQT group was significantly higher than in control
group (p<0.05). On the 3rd and 5th postoperative day, the plasma ghrelin
level in the DCQT group was significantly higher than in the control group
(p<0.05). DCQT could improve gastric dysrythmia, enhance gastrointestinal
motility and adjust the synchronized recovery of the alimentary tract and
increase plasma ghrelin after abdominal surgery.
Source: Jian W, Heng L, Hui QQ. Effect of Da-Cheng-Qi-Tang on gastrointestinal
motility in patients undergoing laparotomy. Hepatogastroenterology.
2011 Nov-Dec;58(112):1887-92.
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